A breakthrough reference - in the versatile, multimedia format Clinial Gastroenterology and Hepatology presents clinically focused, evidence-based coverage on the diagnosis and treatment of disorders of the digestive tract. An international team of leading experts provides a worldwide perspective on patient management, explaining step-by-step how to apply the latest advances in diagnosis and management. Succinct yet comprehensive explanations provide just the right amount of clinical detail. Plus, a consistent templated format and stunning full-colour art program enable readers to quickly and easily access the specific information they need.

Written by a global selection of some of the most exciting names in gastroenterology and hepatology today, Clinical Gastroenterology and Hepatology will be an essential addition to the libraries of gastroenterologists, hepatologists and internists, and particularly trainees and residents who are looking for a modern and fresh approach to this subject area.

The e-dition includes this innovative book and a constantly updated website that allows you to search the complete text from any location and download material to your handheld for use offline.

THE WEBSITE

• Incorporates the text with a state-of-the-art, dedicated website...featuring fully searchable contents of the printed book.
• Includes more than 70 video clips depicting everything from endoscopic clips through instruction on performing the perfect liver biopsy....to virtual endoscopy.
• Features weekly content updates personally edited by the book's lead authors · reference links to MEDLINE abstracts · and links from every drug to complete information in Mosby's Drug Consult.
• Includes POCKETConsult technology that allows you to download updates to your handheld device, and more.
• Includes all of the artwork from the text downloadable into PowerPoint® presentations.

• Includes full-chapter coverage of the hottest topics in today's practice, including Capsule Endoscopy · Virtual Endoscopy Imaging · GERD · Colorectal Cancer: Screening and Surveillance · and Inflammatory Bowel Disease.
• Features more than 1,650 color algorithms, graphs, tables, and photographs that depict today's practice in action.
• Offers just enough information on basic science to provide an understanding of the clinical information presented while avoiding information overload.
• Provides a separate section on diagnosis and treatment.
• Summarizes Causes and Risk Factors/Clinical Presentation and Symptoms/Clinical Pearls/Diagnostic Methods/Differential Diagnosis/Treatment and Prevention/Complications and their Management in boxes found in every chapter.

Part One: SYMPTOMS, SYNDROMES AND SCENARIOS
Discomfort above the diaphragm
1. Differential diagnosis and management of burning mouth syndrome (BMS)
2. Heartburn and non-cardiac chest pain
3. Dysphagia and odynophagia
Discomfort below the diaphragm
4. Chronic or recurrent abdominal pain
5. Dyspepsia
6. Nausea and vomiting
7. Bloating and early satiety
8. Belching and rumination
Disorders of defecation
9. Diarrhea including acute, chronic and bloody
10. Fecal incontinence
11. Rectal bleeding
12. Anorectal pain
Generalized ill health
13. Anorexia and eating disorders
14. Weight loss
15. Gastrointestinal causes of anemia and occult bleeding
16. Pruritus
17. Jaundice
18. Spotting and dealing with signs of chronic liver disease
19. Ascites
20. Abnormal liver function tests
Urgent situations
21. Acute abdominal pain
22. Hematemesis and melena
23. Acute lower gastrointestinal bleeding
Scenarios
24. Being infected with H. pylori
25. Being on NSAIDs
26. Gastrointestinal problems in primary care
27. Gastrointestinal problems in the elderly
28. Gastrointestinal problems in pediatrics
Part Two: DISEASES OF THE GUT AND LIVER
I. DISORDERS OF THE UPPER GASTROINTESTINAL TRACT
Esophageal: benign
29. Gastroesophageal reflux disease (GERD) including hiatus hernia and esophagitis
30. Benign esophageal strictures and caustic esophageal injury
Esophageal: malignant and premalignant
31. Barrett's esophagus
32. Esophageal cancer
Upper gastrointestinal infections
33. Infections of the esophagus and stomach
34. H. pylori: Its diseases and management
Gastroduodenal: benign
35. Peptic ulcer
36. Gastritis
Gastroduodenal: malignant and premalignant
37. Adenocarcinoma
38. Gastric lymphoma
39. Gastrointestinal stromal tumor (GIST) and other gastroduodenal tumors
Motility disorders
40. Esophageal motility disorders
41. Gastric motility disorders
II. DISORDERS OF THE SMALL AND LARGE BOWEL
Food, nutrition and malabsorption
42. Food allergy and intolerance
43. Maldigestion and malabsorption
44. Celiac sprue
45. Short bowel syndrome
46. Small bowel bacterial overgrowth
47. Bile acid malabsorption
48. Protein-losing disorders of the gastrointestinal tract
Intestinal infections and infestations
49. Infective diarrhea
50. Travelers' diarrhea
51. Abdominal tuberculosis
52. Parasites
Inflammatory bowel disease
53. Ulcerative colitis
54. Crohn's disease
55. Indeterminate colitis
56. Microscopic colitis
57. Eosinophilic gastroenteritis
58. Pseudomembranous colitis
59. Ischemia and ischemic colitis
Malignant tumors
60a. Biology and genetics of colorectal cancer
60b. Colorectal cancer: screening and surveillance
60c. Polyps and polyposis
60d. Team approach to cancer management

61. Other gastrointestinal tumors
Motility disorders
62. Obstruction and volvulus
63. Constipation and constipation syndromes
64. Irritable bowel syndrome
65. Diverticular disease of the colon
66. Disorders of colorectal dysmotility
Other disorders of the small and large bowel
67. Splanchnic vascular disorders
68. Drug-induced damage to the small and large intestines
69. Appendicitis
Anorectal disorders
70. Anorectal diseases
III. DISEASES OF THE PANCREAS AND BILIARY TRACT
Pancreas
71. Acute pancreatitis
72. Chronic pancreatitis
73. Pancreatic exocrine tumors
74. Cysts of the pancreas
75. Development and miscellaneous abnormalities

Biliary tract
76. Cholelithiasis, choledocholithiasis and cholecystitis
77. Sphincter of Oddi dysfunction
78. Primary sclerosing cholangitis
79. Cholangiocarcinoma
Malformations
80. Congenital abnormalities of the biliary tract
IV. LIVER DISEASE
Infections
81. Acute viral hepatitis
82a. Chronic viral hepatitis B
82b. Chronic viral hepatitis C
82c. Chronic viral hepatitis D
83. Schistosoma and other parasites
84. Bacterial and fungal infections of the liver
Auto-immune and related disorders
85. Primary biliary cirrhosis
86. Chronic autoimmune hepatitis and overlap syndrome
Genetic and metabolic liver diseases
87. Alcoholic liver diseases
88. Nonalcoholic steatohepatitis (NASH)
89. Hemochromatosis
90. Alpha-1 antitrypsin deficiency
91. Wilson's disease

92. Drug-induced and toxic liver disease
93. Genetic and metabolic liver diseases of childhood

94. Disturbances of bilirubin metabolism
Cirrhosis of the liver and its complications
95. Cirrhosis of the liver
96. Portal hypertension

97. Ascites and hepatorenal syndrome
98. Spontaneous bacterial peritonitis
99. Hepatopulmonary syndrome and portopulmonary hypertension
100. Episodic encephalopathy
101. Fulminant liver failure and acute encephalopathy

Other liver diseases
102. Tumors of the liver

103. Vascular disorders of the liver
104. Granulomas of the liver
105. Liver diseases and pregnancy
Liver transplantation
106. Liver transplantation: indications and selection of candidates and immediate complications
107. Long-term management and recurrence of primary liver disease

V. DISEASES OF MULTIPLE ORGAN SYSTEMS
108. Gastrointestinal tract in systemic disease
109. Gut/pancreatic endocrine tumors
110. The carcinoid syndrome
111. AIDS and the gut
112. Graft-versus-host disease
113. Radiation and other physico-chemical injury
114. Amyloidosis
115. Foreign bodies
116. Porphyria
VI. ABDOMINAL WALL AND CAVITY
117. Abscesses and other intra-abdominal diseases
118. Hernias and the abdominal wall
Part Three: PRIMER OF DIAGNOSTIC METHODS
Endoscopic imaging
119. Upper gastrointestinal endoscopy and mucosal biopsy
120. Lower gastrointestinal endoscopy and mucosal biopsy
121. Endoscopic ultrasound
122. Diagnostic and interventional endoscopic retrograde cholangiopancreatography (ERCP)

123. Capsule endoscopy
Percutaneous imaging
124. Percutaneous ultrasound
125. Barium radiology
126. Computed tomography (CT)
127. Magnetic resonance imaging (MRI)

128. Magnetic resonance cholangiopancreatography (MRCP)
129. Virtual endoscopy imaging
130. Positron emission tomography (PET)

Functional testing
131. Functional evaluation of the gastrointestinal tract
132. Motility testing
133. Measurement of portal pressure

Tissue testing
134. Liver biopsy

135. Histopathology primer for gastroenterologists and hepatologists
Part Four: PRIMER OF TREATMENTS
Medical treatments
136. Drugs used in gastrointestinal and liver disease
137. Drug prescription in liver disease
138. An approach to nutritional assessment
139. Nutrition support
140. Complementary medicine for irritable and inflammatory bowel
Therapeutic endoscopy
141. Conscious sedation
142. Sclerotherapy, banding and other hemostatic techniques for varices and other lesions
143. Photodynamic therapy (PDT)
144. Percutaneous endoscopic gastrostomy (PEG) and jejunostomy
145. Endoscopic resection of tumors and polyps
146. Dilation and stenting of the gastrointestinal tract

Percutaneous therapy
147. The transjugular intrahepatic portosystemic shunt (TIPS)
148. Interventional radiology
149. Paracentesis
A synopsis of surgical operations
150. Liver operations
151. Gastrointestinal operations
152. Minimally invasive surgery

By Wilfred M. Weinstein, MD, Professor of Medicine, Digestive Diseases,David Geffen School of Medicine at UCLA, Los Angeles, CA; Christopher J. Hawkey, DM, FRCP, Professor of Gastroenterology, Wolfson Digestive Diseases Centre, University Hospital, Nottingham, UK; and Jaime Bosch, MD, Professor of Medicine, Liver Unit, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, University of Barcelona, Spain